3-(2-Hydroxyethyl)benzonitrile → 3-[2-(1-Methyl-6-oxo-1,3,4,6-tetrahydro-2H-pyrimido[1,6-a]pyrimidin-8-yloxy)-ethyl]-benzonitrile
反応式
[OH:1][CH2:2][CH2:3][C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[C:7]#[N:8].Cl[C:13]1[CH:23]=[C:17]2[N:18]([CH3:22])[CH2:19][CH2:20][CH2:21][N:16]2[C:15](=[O:24])[N:14]=1>>[CH3:22][N:18]1[CH2:19][CH2:20][CH2:21][N:16]2[C:15](=[O:24])[N:14]=[C:13]([O:1][CH2:2][CH2:3][C:4]3[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=3)[C:7]#[N:8])[CH:23]=[C:17]12参加物
3
実験手順
The title compound or its salt was prepared by a procedure similar to that described for E11 starting from of 3-(2-hydroxyethyl)benzonitrile and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.
出典と根拠
- ORDレコード
- ord-c1aa4f1b9fc04bf18c88673e4e461bed
- 出典データセット
- uspto-grants-2016_03
- 特許番号
- US09273054B2
反応ノート
読み込み中…