(4-Amino-3-chlorophenyl)dimethylphosphine oxide → N2-[2-chloro-4-(dimethylphosphoryl)phenyl]-N4-[2-(propan-2-ylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine-2,4-diamine
反応式
Cl[C:2]1[CH:7]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[S:15]([CH:18]([CH3:20])[CH3:19])(=[O:17])=[O:16])[C:5]([C:21]([F:24])([F:23])[F:22])=[CH:4][N:3]=1.[Cl:25][C:26]1[CH:32]=[C:31]([P:33]([CH3:36])([CH3:35])=[O:34])[CH:30]=[CH:29][C:27]=1[NH2:28]>>[Cl:25][C:26]1[CH:32]=[C:31]([P:33]([CH3:35])([CH3:36])=[O:34])[CH:30]=[CH:29][C:27]=1[NH:28][C:2]1[CH:7]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[S:15]([CH:18]([CH3:20])[CH3:19])(=[O:16])=[O:17])[C:5]([C:21]([F:24])([F:22])[F:23])=[CH:4][N:3]=1参加物
3
実験手順
This compound can be prepared as described in Example 80 by reacting 2-chloro-N-[2-(propan-2-ylsulfonyl)phenyl]-5-(trifluoromethyl)pyridin-4-amine with 2-chloro-4-(dimethylphosphoryl)-aniline.
後処理
- customThis compound can be prepared