HCID 14245847、化合物 → HCID 428467、化合物

HRID 921511ノート

反応式

HRID 921511 の反応式
[H-].[H-].[H-].[H-].[Li+].[Al+3].[CH:7]([NH:9][CH2:10][C:11]([CH3:17])([CH3:16])[CH2:12][NH:13][CH:14]=O)=O>CCOCC>[CH3:7][NH:9][CH2:10][C:11]([CH3:17])([CH3:16])[CH2:12][NH:13][CH3:14]

参加物

4

反応物 2

HCID 14245847HCID 14245847、化合物HCID 21226445Aluminium lithium hydride

生成物 1

HCID 428467HCID 428467、化合物

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

To a mixture of 250 mL of ether and 10 g of LiAlH4 (95%) at 0° C., 9.88 g (62.5 mmol) N,N′-diformyl-2,2-dimethylpropane-1,3-diamine was added in small portions. After the addition, the reaction mixture was stirred at room temperature for 20 h. The mixture was then hydrolyzed with ether and water, the white solid removed by filtration through Celite, and the filtrate dried over anhydrous Na2SO4. After removal of the solvent, the product was obtained as a colorless oil. MS (m/e): 131 (M+).

後処理

  1. additionAfter the addition
  2. customhydrolyzed with ether and water, the white solid removed by filtration through Celite
  3. dry with materialthe filtrate dried over anhydrous Na2SO4
  4. customAfter removal of the solvent
  5. customthe product was obtained as a colorless oil

出典と根拠

ORDレコード
ord-cf41ee942e22437eb95d69e2f78610fb
出典データセット
uspto-grants-2016_03
特許番号
US09273343B2

反応ノート

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