O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate → (S)-(3R,4R)-1-(2-chloro-5-cyano-3-((7-cyano-4-(ethylamino)imidazo[2,1-f][1,2,4]triazin-2-yl)amino)phenyl)-4-((methoxycarbonyl)amino)piperidin-3-yl 2-((S)-2,6-bis((tert-butoxycarbonyl)amino)hexanamido)-3-methylbutanoate

反応式

[C:1]([O:5][C:6]([NH:8][C@@H:9]([CH2:13][CH2:14][CH2:15][CH2:16][NH:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[C:10]([OH:12])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].CN(C(ON1N=NC2C=CC=CC1=2)=[N+](C)C)C.[B-](F)(F)(F)F.Cl.Cl.[NH2:49][C@@H:50]([CH:89]([CH3:91])[CH3:90])[C:51]([O:53][C@H:54]1[C@H:59]([NH:60][C:61]([O:63][CH3:64])=[O:62])[CH2:58][CH2:57][N:56]([C:65]2[CH:70]=[C:69]([C:71]#[N:72])[CH:68]=[C:67]([NH:73][C:74]3[N:79]=[C:78]([NH:80][CH2:81][CH3:82])[C:77]4=[N:83][CH:84]=[C:85]([C:86]#[N:87])[N:76]4[N:75]=3)[C:66]=2[Cl:88])[CH2:55]1)=[O:52]>C(Cl)Cl>[C:1]([O:5][C:6]([NH:8][C@@H:9]([CH2:13][CH2:14][CH2:15][CH2:16][NH:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[C:10]([NH:49][C@@H:50]([CH:89]([CH3:90])[CH3:91])[C:51]([O:53][C@H:54]1[C@H:59]([NH:60][C:61]([O:63][CH3:64])=[O:62])[CH2:58][CH2:57][N:56]([C:65]2[CH:70]=[C:69]([C:71]#[N:72])[CH:68]=[C:67]([NH:73][C:74]3[N:79]=[C:78]([NH:80][CH2:81][CH3:82])[C:77]4=[N:83][CH:84]=[C:85]([C:86]#[N:87])[N:76]4[N:75]=3)[C:66]=2[Cl:88])[CH2:55]1)=[O:52])=[O:12])=[O:7])([CH3:2])([CH3:3])[CH3:4]