5-Bromo-6-chloropyridine-3-carboxylic acid → HCID 86702634、化合物
反応式
[Br:1][C:2]1[C:3]([Cl:11])=[N:4][CH:5]=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[F:12][C:13]([F:23])([F:22])[S:14][C:15]1[N:20]=[CH:19][C:18]([NH2:21])=[CH:17][CH:16]=1>>[Br:1][C:2]1[C:3]([Cl:11])=[N:4][CH:5]=[C:6]([CH:10]=1)[C:7]([NH:21][C:18]1[CH:19]=[N:20][C:15]([S:14][C:13]([F:23])([F:22])[F:12])=[CH:16][CH:17]=1)=[O:9]参加物
3
実験手順
The title compound was prepared in an analogous fashion to that described in Stage 169.2 using 5-bromo-6-chloronicotinic acid and 6-(trifluoromethylthio)pyridin-3-amine to afford an off-white powder. HPLC (Condition 4) tR=6.43 min, UPLC-MS (Condition 3) tR=1.15 min, m/z=411.9 [M−H]−.
後処理
- customto afford an off-white powder
出典と根拠
- ORDレコード
- ord-114abcb110294bfbaaa45691b0441209
- 出典データセット
- uspto-grants-2016_03
- 特許番号
- US09278981B2
反応ノート
読み込み中…