1-methyl-1H-pyrrole-3-carboxylic acid → (1-{4-[(1-isopropylpiperidin-4-yl)oxy]phenyl}-1H-pyrrol-3-yl)(pyrroldin-1-yl)methanone

反応式

CN1C=CC(C(O)=O)=C1.[NH:10]1[CH:14]=[CH:13][C:12]([C:15]([N:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)=[O:16])=[CH:11]1.[CH:22]1([N:26]2[CH2:31][CH2:30][CH:29]([O:32][C:33]3[CH:38]=[CH:37][C:36](I)=[CH:35][CH:34]=3)[CH2:28][CH2:27]2)[CH2:25]C[CH2:23]1.IC1C=CC(OC2CCN(C(C)C)CC2)=CC=1>>[CH:22]([N:26]1[CH2:31][CH2:30][CH:29]([O:32][C:33]2[CH:34]=[CH:35][C:36]([N:10]3[CH:14]=[CH:13][C:12]([C:15]([N:17]4[CH2:21][CH2:20][CH2:19][CH2:18]4)=[O:16])=[CH:11]3)=[CH:37][CH:38]=2)[CH2:28][CH2:27]1)([CH3:25])[CH3:23]