戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 927082作成日：2026年10月26日

2-Fluoro-5-iodotoluene → 3,4-Bis(benzyloxy)-6-[2-(4-fluoro-3-methylphenyl)ethynyl]pyridazine

https://huagongshe.com/reaction/927082

反応式

関与物質

役割名称HCID仕込み量
反応物2-Fluoro-5-iodotolueneHCID 521178—
反応物3,4-Bis(benzyloxy)-6-{[5-(trifluoromethyl)pyridin-2-yl]ethynyl}pyridazineHCID 71269910—
反応物3,4-Bis(benzyloxy)-6-ethynylpyridazineHCID 86677025—
生成物3,4-Bis(benzyloxy)-6-[2-(4-fluoro-3-methylphenyl)ethynyl]pyridazineHCID 7127036967%

反応手順

Prepared as described for 3,4-bis(benzyloxy)-6-{[5-(trifluoromethyl)pyridin-2-yl]ethynyl}pyridazine (Intermediate 6) from 3,4-bis(benzyloxy)-6-ethynylpyridazine (Intermediate 5) and 1-fluoro-4-iodo-2-methylbenzene in 67% yield.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09290456B2
出典データセットuspto-grants-2016_03
ORD IDord-94a8618523ab4b7a8ec572cad712a576
出典メモuspto-grants-2016_03