化工社化工社 化学情報印刷レポート · 研究参考用
4-Iodo-1,2-dimethoxybenzene → 3,4-bis(Benzyloxy)-6-[2-(3,4-dimethoxyphenyl)ethynyl]pyridazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Iodo-1,2-dimethoxybenzene | HCID 230307 | — |
| 反応物 | 3,4-Bis(benzyloxy)-6-{[5-(trifluoromethyl)pyridin-2-yl]ethynyl}pyridazine | HCID 71269910 | — |
| 反応物 | 3,4-Bis(benzyloxy)-6-ethynylpyridazine | HCID 86677025 | — |
| 生成物 | 3,4-bis(Benzyloxy)-6-[2-(3,4-dimethoxyphenyl)ethynyl]pyridazine | HCID 71270121 | 17% |
反応手順
Prepared as described for 3,4-bis(benzyloxy)-6-{[5-(trifluoromethyl)pyridin-2-yl]ethynyl}pyridazine (Intermediate 6) from 3,4-bis(benzyloxy)-6-ethynylpyridazine (Intermediate 5) and 4-iodo-1,2-dimethoxybenzene in 17% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09290456B2 |
| 出典データセット | uspto-grants-2016_03 |
| ORD ID | ord-10bb13aa6f14400a9d4fed4e9ef9142b |
| 出典メモ | uspto-grants-2016_03 |