3,4-Bis(benzyloxy)-6-((2-chlorophenyl)ethynyl)pyridazine → HCID 178518811、化合物
反応式
OC1C(=O)NN=C(CCC2C=CC=CC=2)C=1.C([O:24][C:25]1[N:26]=[N:27][C:28]([C:39]#[C:40][C:41]2[CH:46]=[CH:45][CH:44]=[CH:43][C:42]=2[Cl:47])=[CH:29][C:30]=1[O:31]CC1C=CC=CC=1)C1C=CC=CC=1>C(OCC)(=O)C>[Cl:47][C:42]1[CH:43]=[CH:44][CH:45]=[CH:46][C:41]=1[CH2:40][CH2:39][C:28]1[CH:29]=[C:30]([OH:31])[C:25](=[O:24])[NH:26][N:27]=1参加物
4
実験手順
Prepared by the same method as for 4-hydroxy-6-(2-phenylethyl)pyridazin-3(2H)-one (Example 1) from 3,4-bis(benzyloxy)-6-((2-chlorophenyl)ethynyl)pyridazine (Intermediate 35) except that the solvent used for the hydrogenation was ethyl acetate and the final material was recrystallised from a mixture of ethyl acetate and heptane
後処理
- customthe final material was recrystallised from a mixture of ethyl acetate and heptane
出典と根拠
- ORDレコード
- ord-6ca1416ed677457c99dc345afc2e3fed
- 出典データセット
- uspto-grants-2016_03
- 特許番号
- US09290456B2
反応ノート
読み込み中…