Hydrochloric Acid → 2-Amino-2-ethyl-N,N-dimethylbutanamide hydrogen chloride

HRID 927379ノート

反応式

HRID 927379 の反応式
[CH3:1][N:2]([CH3:18])[C:3]([C:5]([NH:10]C(=O)OC(C)(C)C)([CH2:8][CH3:9])[CH2:6][CH3:7])=[O:4].[ClH:19]>C(OCC)(=O)C>[ClH:19].[NH2:10][C:5]([CH2:8][CH3:9])([CH2:6][CH3:7])[C:3]([N:2]([CH3:18])[CH3:1])=[O:4]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 86674741tert-Butyl 3-(dimethylcarbamoyl)pentan-3-ylcarbamate

生成物 1

HCID 866747422-Amino-2-ethyl-N,N-dimethylbutanamide hydrogen chloride

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

tert-Butyl 3-(dimethylcarbamoyl)pentan-3-ylcarbamate (0.12 g, 0.47 mmol) was added to a saturated solution of hydrochloride in ethyl acetate (5 mL) and the mixture was stirred overnight. The solvent was removed by reduced pressure to give the crude product (0.1 g); MS (EI): m/e=159.2 [M+H]+.

後処理

  1. customThe solvent was removed by reduced pressure

出典と根拠

ORDレコード
ord-ac4de43200e841b2a623fc48f4a3fcb0
出典データセット
uspto-grants-2016_03
特許番号
US09290451B2

反応ノート

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