Hydrochloric Acid → 3-Amino-3-methyl-1-morpholinobutan-1-one hydrochloride

HRID 927405ノート

反応式

HRID 927405 の反応式
[CH3:1][C:2]([NH:13]C(=O)OC(C)(C)C)([CH2:4][C:5]([N:7]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1)=[O:6])[CH3:3].[ClH:21]>C(OCC)(=O)C>[ClH:21].[NH2:13][C:2]([CH3:3])([CH3:1])[CH2:4][C:5]([N:7]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1)=[O:6]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 71105557tert-Butyl 2-methyl-4-morpholino-4-oxobutan-2-ylcarbamate

生成物 1

HCID 710876483-Amino-3-methyl-1-morpholinobutan-1-one hydrochloride

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

tert-Butyl 2-methyl-4-morpholino-4-oxobutan-2-ylcarbamate (0.5 g, 1.7 mmol) was dissolved in a saturated solution of hydrogen chloride in ethyl acetate (20 mL). The mixture was stirred for 3 h. The solvent was removed by reduced pressure to give crude product (0.55 g).

後処理

  1. customThe solvent was removed by reduced pressure

出典と根拠

ORDレコード
ord-6de459a3fc17439788976df2698c278d
出典データセット
uspto-grants-2016_03
特許番号
US09290451B2

反応ノート

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