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HRID 927674作成日：2026年10月27日

5-Cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carboxylic acid → 2-{[5-Cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carbonyl]-amino}-2-ethyl-butyric acid methyl ester

https://huagongshe.com/reaction/927674

反応式

関与物質

役割名称HCID仕込み量
反応物5-Cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carboxylic acidHCID 71087254—
反応物Methyl 2-amino-2-ethylbutanoate hydrochlorideHCID 75488114—
生成物2-{[5-Cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carbonyl]-amino}-2-ethyl-butyric acid methyl esterHCID 71087666—

反応手順

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carboxylic acid (Example 166 b) and methyl 2-amino-2-ethylbutanoate hydrochloride (CAN 92398-54-4) as starting materials, MS (EI): m/e=391.3 [M+H]+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09290451B2
出典データセットuspto-grants-2016_03
ORD IDord-bcca540f443045bc8275dd525c88daa7
出典メモuspto-grants-2016_03