化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl 2-amino-2-ethylbutanoate hydrochloride → 2-[(5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carbonyl)-amino]-2-ethyl-butyric acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl 2-amino-2-ethylbutanoate hydrochloride | HCID 24201639 | — |
| 反応物 | 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 71087346 | — |
| 生成物 | 2-[(5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carbonyl)-amino]-2-ethyl-butyric acid methyl ester | HCID 71087351 | — |
反応手順
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethyloxy-pyridine-2-carboxylic acid (Example 42a) and 2-amino-2-ethyl-butanoic acid ethyl ester hydrochloride (1:1) (CAN 70974-26-4) as starting materials, LC-MS (UV peak area/ESI) 100%, 361.2120 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09290451B2 |
| 出典データセット | uspto-grants-2016_03 |
| ORD ID | ord-a3d7358351ae4f0796048d0a408a2a2c |
| 出典メモ | uspto-grants-2016_03 |