N-((S)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride → N-((R)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride

HRID 928008ノート

反応式

HRID 928008 の反応式
[ClH:1].Cl.[CH2:3]([N:5]1[CH2:9][CH2:8][C@H:7]([NH:10][CH3:11])[CH2:6]1)[CH3:4].C(N1CC[C@@H](N(C)C(=O)OCC2C=CC=CC=2)C1)C>>[ClH:1].[ClH:1].[CH2:3]([N:5]1[CH2:9][CH2:8][C@@H:7]([NH:10][CH3:11])[CH2:6]1)[CH3:4]

参加物

3

反応物 2

HCID 86713333N-((S)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochlorideHCID 86713337benzyl N-((R)-1-ethylpyrrolidin-3-yl)-N-methylcarbamate2 回

生成物 1

HCID 86713336N-((R)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride

実験手順

Prepared by proceeding in a similar manner to Intermediate 127, starting from benzyl N—((R)-1-ethylpyrrolidin-3-yl)-N-methylcarbamate (Intermediate 133) as a light coloured viscous oil, which was used without further characterization.

後処理

  1. customPrepared

出典と根拠

ORDレコード
ord-74d3b56d67514f0fb685f0929e5dddcd
出典データセット
uspto-grants-2016_03
特許番号
US09290472B2

反応ノート

読み込み中…