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HRID 928744作成日：2026年10月26日

3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-2,4-dichloroquinoline → 3-(4-(1H-Pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinoline

https://huagongshe.com/reaction/928744

反応式

関与物質

役割名称HCID仕込み量
反応物3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-2,4-dichloroquinolineHCID 86715594—
反応物3-(4-(1H-Pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxyquinolineHCID 86715596—
反応物3-(4-(1H-Pyrazol-1-yl)benzyl)-6-bromo-2,4-dichloro-8-methylquinolineHCID 86715598—
生成物3-(4-(1H-Pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinolineHCID 86715599—

反応手順

The title compound was prepared by using 3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-2,4-dichloro-8-methylquinoline (Intermediate 19: step a) in place of 3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-2,4-dichloroquinoline (Intermediate 6: step c) then following the procedure described for the preparation of 3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxyquinoline (Intermediate 16).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09290476B2
出典データセットuspto-grants-2016_03
ORD IDord-35e8a3c00e8946468ea434871f810c01
出典メモuspto-grants-2016_03