HCID 66687731、化合物 → 1-[5-(3-Bromo-5-methoxy-phenyl)-1-(3-pyridyl)pyrazole-3-carbonyl]imidazolidin-4-one
反応式
[Br:1][C:2]1[CH:3]=[C:4]([C:10]2[N:14]([C:15]3[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=3)[N:13]=[C:12]([C:21]([OH:23])=O)[CH:11]=2)[CH:5]=[C:6]([O:8][CH3:9])[CH:7]=1.ClC1C=C(C2N(C3C=CC=CN=3)N=C(C([N:45]3[CH2:49][C:48](=[O:50])[NH:47][CH2:46]3)=O)C=2)C=C(F)C=1.Cl.N1C=CNC1=O>>[Br:1][C:2]1[CH:3]=[C:4]([C:10]2[N:14]([C:15]3[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=3)[N:13]=[C:12]([C:21]([N:45]3[CH2:49][C:48](=[O:50])[NH:47][CH2:46]3)=[O:23])[CH:11]=2)[CH:5]=[C:6]([O:8][CH3:9])[CH:7]=1参加物
4
実験手順
80 mg (0.21 mmol) of the compound of Example 50A is reacted analogously to the synthesis of the compound of Example 1 with 29 mg (0.24 mmol) of 4-imidazolinone-hydrochloride. 76 mg (79% of theory) of the title compound is obtained.