Dichloromethane → 5-(4-(2-aminopyridin-4-yloxy)-3-fluorophenyl)-3-benzyl-2-(4-fluorophenylamino)pyrimidin-4(3H)-one
反応式
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([NH:23][c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)[n:10][cH:11][c:12](-[c:15]2[cH:16][c:17]([F:22])[c:18]([OH:21])[cH:19][cH:20]2)[c:13]1=[O:14].[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[CH3:46][N:47]1[CH2:48][CH2:49][CH2:50][C:51]1=[O:52].[CH3:53][N:54]([c:55]1[cH:56][cH:57][n:58][cH:59][cH:60]1)[CH3:61].[Cl:31][c:32]1[cH:33][c:34]([NH2:38])[n:35][cH:36][cH:37]1.[Cl:62][CH2:63][Cl:64]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([NH:23][c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)[n:10][cH:11][c:12](-[c:15]2[cH:16][c:17]([F:22])[c:18]([O:21][c:32]3[cH:33][c:34]([NH2:38])[n:35][cH:36][cH:37]3)[cH:19][cH:20]2)[c:13]1=[O:14]
