Dimethyl Sulfoxide → 3-{3-Cyano-6-[(2,2-dimethyl-propyl)-methyl-amino]-5-fluoro-pyridin-2-ylamino}-N-methoxy-4-methyl-benzamide

反応式

[CH3:33][S:34]([CH3:35])=[O:36].[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([F:17])[c:8]([N:10]([CH3:11])[CH2:12][C:13]([CH3:14])([CH3:15])[CH3:16])[n:9]1.[F-:31].[K+:32].[NH2:18][c:19]1[cH:20][c:21]([C:22](=[O:23])[NH:24][O:25][CH3:26])[cH:27][cH:28][c:29]1[CH3:30]>>[c:2]1([NH:18][c:19]2[cH:20][c:21]([C:22](=[O:23])[NH:24][O:25][CH3:26])[cH:27][cH:28][c:29]2[CH3:30])[c:3]([C:4]#[N:5])[cH:6][c:7]([F:17])[c:8]([N:10]([CH3:11])[CH2:12][C:13]([CH3:14])([CH3:15])[CH3:16])[n:9]1