Hydroxide → {6-[2-methyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid

反応式

[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][n:6]1[cH:7][cH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH2:16][c:17]3[n:18]([CH3:32])[n:19][c:20](-[c:22]4[cH:23][cH:24][c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]4)[cH:21]3)[cH:13][c:14]12)=[O:33].[Li+:35].[OH-:34]>>[O:3]=[C:4]([CH2:5][n:6]1[cH:7][cH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH2:16][c:17]3[n:18]([CH3:32])[n:19][c:20](-[c:22]4[cH:23][cH:24][c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]4)[cH:21]3)[cH:13][c:14]12)[OH:33]

参加物

反応物 3

HCID 961Hydroxide

HCID 28486Lithium ion

HCID 69280222{6-[2-Methyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid ethyl ester

生成物 1

HCID 11582750{6-[2-methyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid

出典と根拠

ORDレコード: ord-9b07ea62b519485b91c5de86176ea737
出典データセット: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…