Water → 5-[3,5-bis(trifluoromethyl)benzyl]-6-oxo-7-phenyl-9-[4-(pyrrolidine-1-yl)piperidine-1-yl]-2,3,4,5-tetrahydro-6H-pyrido[2,3-b][1,5]oxazocine

反応式

[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:26])[c:9]3[c:10]([n:15][c:16]([Cl:25])[cH:17][c:18]3-[c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[O:11][CH2:12][CH2:13][CH2:14]2)[cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]1)([F:34])[F:35].[N:36]1([CH:41]2[CH2:42][CH2:43][NH:44][CH2:45][CH2:46]2)[CH2:37][CH2:38][CH2:39][CH2:40]1.[OH2:47]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:26])[c:9]3[c:10]([n:15][c:16]([N:44]4[CH2:43][CH2:42][CH:41]([N:36]5[CH2:37][CH2:38][CH2:39][CH2:40]5)[CH2:46][CH2:45]4)[cH:17][c:18]3-[c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[O:11][CH2:12][CH2:13][CH2:14]2)[cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]1)([F:34])[F:35]