4-Methoxybenzylamine → [6,7-Dimethoxy-4-(4-methoxy-benzylcarbamoyl)-isoquinolin-1-ylmethyl]-carbamic acid tert-butyl ester

反応式

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][c:10]1[n:11][cH:12][c:13]([C:24](=[O:25])[OH:26])[c:14]2[cH:15][c:16]([O:22][CH3:23])[c:17]([O:20][CH3:21])[cH:18][c:19]12.[CH3:27][O:28][c:29]1[cH:30][cH:31][c:32]([CH2:33][NH2:34])[cH:35][cH:36]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][c:10]1[n:11][cH:12][c:13]([C:24](=[O:25])[NH:34][CH2:33][c:32]2[cH:31][cH:30][c:29]([O:28][CH3:27])[cH:36][cH:35]2)[c:14]2[cH:15][c:16]([O:22][CH3:23])[c:17]([O:20][CH3:21])[cH:18][c:19]12

参加物

反応物 2

HCID 754524-Methoxybenzylamine

HCID 593410711-(tert-Butoxycarbonylamino-methyl)-6,7-dimethoxy-isoquinoline-4-carboxylic acid

生成物 1

HCID 68614449[6,7-Dimethoxy-4-(4-methoxy-benzylcarbamoyl)-isoquinolin-1-ylmethyl]-carbamic acid tert-butyl ester

出典と根拠

ORDレコード: ord-c95fbc6f0ec646d2a26da40d319273ac
出典データセット: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…