Hydrochloric Acid → (RS)-2-[4-(6-amino-pyridin-3-yl)-2,6-difluoro-phenyl]-N-(4-cyano-2,6-difluoro-benzyl)-2-ethoxy-acetamide

反応式

[ClH:23].[NH2:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([F:22])[c:11]([CH:15]([C:16](=[O:17])[OH:18])[O:19][CH2:20][CH3:21])[c:12]([F:14])[cH:13]2)[cH:6][n:7]1.[NH2:24][CH2:25][c:26]1[c:27]([F:35])[cH:28][c:29]([C:30]#[N:31])[cH:32][c:33]1[F:34]>>[NH2:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([F:22])[c:11]([CH:15]([C:16](=[O:18])[NH:24][CH2:25][c:26]3[c:27]([F:35])[cH:28][c:29]([C:30]#[N:31])[cH:32][c:33]3[F:34])[O:19][CH2:20][CH3:21])[c:12]([F:14])[cH:13]2)[cH:6][n:7]1

参加物

反応物 3

HCID 313Hydrochloric Acid

HCID 21905479(RS)-[4-(6-amino-pyridin-3-yl)-2,6-difluoro-phenyl]-ethoxy-acetic acid

HCID 219055604-(Aminomethyl)-3,5-difluorobenzonitrile

生成物 1

HCID 21905192(RS)-2-[4-(6-amino-pyridin-3-yl)-2,6-difluoro-phenyl]-N-(4-cyano-2,6-difluoro-benzyl)-2-ethoxy-acetamide

出典と根拠

ORDレコード: ord-1a1c7730ee704d679e1f686f311b2828
出典データセット: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…