Acetone → 3-(4-chloro-3-oxo-1,2-dihydro-isoindol-2-yl)-2,3-dihydro-1H-indene-5-carboxylic acid

反応式

[CH3:27][OH:28].[CH3:30][C:31](=[O:32])[CH3:33].[CH3:3][O:4][C:5](=[O:6])[c:7]1[cH:8][c:9]2[c:13]([cH:14][cH:15]1)[CH2:12][CH2:11][CH:10]2[N:16]1[CH2:17][c:18]2[cH:19][cH:20][cH:21][c:22]([Cl:26])[c:23]2[C:24]1=[O:25].[Li+:2].[OH-:1].[OH2:29]>>[O:4]=[C:5]([OH:6])[c:7]1[cH:8][c:9]2[c:13]([cH:14][cH:15]1)[CH2:12][CH2:11][CH:10]2[N:16]1[CH2:17][c:18]2[cH:19][cH:20][cH:21][c:22]([Cl:26])[c:23]2[C:24]1=[O:25]