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HRID 9501作成日：2026年10月23日

N-[2-(4-amino-7-bromo-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)-ethyl]methanesulfonamide → n-[2-(4-Amino-2-butyl-7-vinyl-1h-imidazo[4,5-c]quinolin-1-yl)ethyl]methanesulfonamide

https://huagongshe.com/ja/reaction/9501

反応式

関与物質

役割名称HCID仕込み量
反応物N-[2-(4-amino-7-bromo-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)-ethyl]methanesulfonamideHCID 21984323—
反応物Potassium vinyltrifluoroborateHCID 23679353—
生成物n-[2-(4-Amino-2-butyl-7-vinyl-1h-imidazo[4,5-c]quinolin-1-yl)ethyl]methanesulfonamideHCID 21984133—

反応手順

N-[2-(4-Amino-7-bromo-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)ethyl]methanesulfonamide was coupled with potassium vinyltrifluoroborate according to the procedure described in Part D of Examples 440–455 and recrystallized from acetonitrile to provide N-[2-(4-amino-2-butyl-7-vinyl-1H-imidazo[4,5-c]quinolin-1-yl)ethyl]methanesulfonamide as an off-white solid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07091214B2
出典データセットuspto-grants-2006_08
ORD IDord-3930a4c368c440b2ab323231484fcfea
出典メモuspto-grants-2006_08