4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid → N-(3-methylimidazo[1,2-a]pyridin-6-yl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxamide

反応式

[CH3:1][c:2]1[cH:3][n:4][c:5]2[n:6]1[cH:7][c:8]([N+:11]([O-:12])=[O:13])[cH:9][cH:10]2.[F:14][C:15]([c:16]1[cH:17][cH:18][c:19](-[c:22]2[cH:23][cH:24][c:25]([C:28](=[O:29])[OH:30])[cH:26][cH:27]2)[cH:20][cH:21]1)([F:31])[F:32]>>[CH3:1][c:2]1[cH:3][n:4][c:5]2[n:6]1[cH:7][c:8]([NH:11][C:28]([c:25]1[cH:24][cH:23][c:22](-[c:19]3[cH:18][cH:17][c:16]([C:15]([F:14])([F:31])[F:32])[cH:21][cH:20]3)[cH:27][cH:26]1)=[O:29])[cH:9][cH:10]2

参加物

反応物 2

HCID 27827194'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid

HCID 218273463-Methyl-6-nitroimidazo[1,2-a]pyridine

生成物 1

HCID 57594110N-(3-methylimidazo[1,2-a]pyridin-6-yl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxamide

出典と根拠

ORDレコード: ord-a3deb4e91dbd4e0c9754e91519ad7676
出典データセット: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…