N-Boc-5-bromoindole → 5-[(1-Tert-butoxycarbonyl-2-propyl-pyrrolidin-2-yl)-hydroxy-methyl]-indole-1-carboxylic acid tert-butyl ester

反応式

[C:18]([Li:19])([CH3:20])([CH3:21])[CH3:22].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[cH:9][cH:10][c:11]2[cH:12][c:13]([Br:17])[cH:14][cH:15][c:16]12.[C:23]([CH3:24])([CH3:25])([CH3:26])[O:27][C:28](=[O:29])[N:30]1[C:31]([CH2:35][CH2:36][CH3:37])([CH:38]=[O:39])[CH2:32][CH2:33][CH2:34]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[cH:9][cH:10][c:11]2[cH:12][c:13]([CH:38]([C:31]3([CH2:35][CH2:36][CH3:37])[N:30]([C:28]([O:27][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:29])[CH2:34][CH2:33][CH2:32]3)[OH:39])[cH:14][cH:15][c:16]12