2-(2-Amino-1-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-7-ylamino)-ethanol → 2-{2-[5-Chloro-4-(2-methoxy-4-morpholin-4-yl-phenylamino)-pyrimidin-2-ylamino]-1-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-7-ylamino]-ethanol

反応式

[Cl:19][c:20]1[n:21][cH:22][c:23]([Cl:41])[c:24]([NH:26][c:27]2[c:28]([O:39][CH3:40])[cH:29][c:30]([N:33]3[CH2:34][CH2:35][O:36][CH2:37][CH2:38]3)[cH:31][cH:32]2)[n:25]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([c:16]1[O:17][CH3:18])[CH2:7][CH2:8][CH:9]([NH:12][CH2:13][CH2:14][OH:15])[CH2:10][CH2:11]2>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([c:16]1[O:17][CH3:18])[CH2:7][CH2:8][CH:9]([NH:12][CH2:13][CH2:14][OH:15])[CH2:10][CH2:11]2)[c:20]1[n:21][cH:22][c:23]([Cl:41])[c:24]([NH:26][c:27]2[c:28]([O:39][CH3:40])[cH:29][c:30]([N:33]3[CH2:34][CH2:35][O:36][CH2:37][CH2:38]3)[cH:31][cH:32]2)[n:25]1

参加物

反応物 2

HCID 672638882-(2-Amino-1-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-7-ylamino)-ethanol

HCID 86633851(2,5-Dichloropyrimidin-4-yl)-(2-methoxy-4-morpholin-4-yl-phenyl)-amine

生成物 1

HCID 668305012-{2-[5-Chloro-4-(2-methoxy-4-morpholin-4-yl-phenylamino)-pyrimidin-2-ylamino]-1-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-7-ylamino]-ethanol

出典と根拠

ORDレコード: ord-f9fb71aa3df64e43ac23863ff7cff75f
出典データセット: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…