5-amino-N-cyclopropyl-2,4-difluorobenzamide → 6-{5-[(5-Cyclopropylcarbamoyl-2,4-difluoro-phenylamino)-methyl]-thiazol-2-ylamino}-nicotinic acid

HRID 955534

反応式

[CH:1](=[O:2])[c:3]1[cH:4][n:5][c:6]([NH:8][c:9]2[n:10][cH:11][c:12]([C:13](=[O:14])[OH:15])[cH:16][cH:17]2)[s:7]1.[NH2:18][c:19]1[c:20]([F:32])[cH:21][c:22]([F:31])[c:23]([C:24](=[O:25])[NH:26][CH:27]2[CH2:28][CH2:29]2)[cH:30]1>>[CH2:1]([c:3]1[cH:4][n:5][c:6]([NH:8][c:9]2[n:10][cH:11][c:12]([C:13](=[O:14])[OH:15])[cH:16][cH:17]2)[s:7]1)[NH:18][c:19]1[c:20]([F:32])[cH:21][c:22]([F:31])[c:23]([C:24](=[O:25])[NH:26][CH:27]2[CH2:28][CH2:29]2)[cH:30]1