Bicarbonate Ion → rac-(2S,3R,4S)-4-(3-chloro-2-fluoro-phenyl)-3-(4-chloro-2-fluoro-phenyl)-3-cyano-2-(2,2-dimethyl-propyl)-pyrrolidine-1-carbonyl chloride
反応式
[Cl:1][c:2]1[c:3]([F:28])[c:4]([CH:8]2[C:9]([C:18]#[N:19])([c:20]3[c:21]([F:27])[cH:22][c:23]([Cl:26])[cH:24][cH:25]3)[CH:10]([CH2:13][C:14]([CH3:15])([CH3:16])[CH3:17])[NH:11][CH2:12]2)[cH:5][cH:6][cH:7]1.[Cl:34][C:35]([Cl:36])=[O:37].[Cl:38][CH2:39][Cl:40].[Na+:33].[O-:29][C:30]([OH:31])=[O:32]>>[Cl:1][c:2]1[c:3]([F:28])[c:4]([CH:8]2[C:9]([C:18]#[N:19])([c:20]3[c:21]([F:27])[cH:22][c:23]([Cl:26])[cH:24][cH:25]3)[CH:10]([CH2:13][C:14]([CH3:15])([CH3:16])[CH3:17])[N:11]([C:35]([Cl:34])=[O:37])[CH2:12]2)[cH:5][cH:6][cH:7]1
