Dimethylformamide → 3-tert-butoxycarbonyl-7-chloro-6-[2-(cyclopropylmethyl-amino)-thiazol-5-ylthiomethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepine

反応式

[Br:22][c:23]1[cH:24][n:25][c:26]([NH:28][CH2:29][CH:30]2[CH2:31][CH2:32]2)[s:27]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][c:11]2[c:12]([c:15]([CH2:20][SH:21])[c:16]([Cl:19])[cH:17][cH:18]2)[CH2:13][CH2:14]1.[C:33](=[O:34])([O-:35])[O-:36].[Cs+:37].[Cs+:38].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][c:11]2[c:12]([c:15]([CH2:20][S:21][c:23]3[cH:24][n:25][c:26]([NH:28][CH2:29][CH:30]4[CH2:31][CH2:32]4)[s:27]3)[c:16]([Cl:19])[cH:17][cH:18]2)[CH2:13][CH2:14]1