N-Benzyl-N-methylpiperidin-4-amine → Benzyl-[1-(2-chloro-4-morpholin-4-yl-thieno[2,3-d]pyrimidin-6-ylmethyl)-piperidin-4-yl]-methyl-amine

反応式

[CH2:19]([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[N:26]([CH:27]1[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]1)[CH3:33].[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH:11]=[O:12])[cH:10]2>>[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH2:11][N:30]1[CH2:29][CH2:28][CH:27]([N:26]([CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[CH3:33])[CH2:32][CH2:31]1)[cH:10]2

参加物

反応物 2

HCID 1096081N-Benzyl-N-methylpiperidin-4-amine

HCID 568338442-Chloro-4-morpholinothieno[2,3-d]pyrimidine-6-carbaldehyde

生成物 1

HCID 86623567Benzyl-[1-(2-chloro-4-morpholin-4-yl-thieno[2,3-d]pyrimidin-6-ylmethyl)-piperidin-4-yl]-methyl-amine

出典と根拠

ORDレコード: ord-2b5d92d66dac4316a41886a3639a62d8
出典データセット: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…