Chlorine → 2-Chloro-5H-dibenzo[b,e]azepine-6,11-dione
反応式
[Cl:1]Cl.[CH:3]1[C:13]2[C:12](=[O:14])[C:11]3[CH:15]=[CH:16][CH:17]=[CH:18][C:10]=3[C:9](=[O:19])[NH:8][C:7]=2[CH:6]=[CH:5][CH:4]=1>C(O)(=O)C>[Cl:1][C:4]1[CH:5]=[CH:6][C:7]2[NH:8][C:9](=[O:19])[C:10]3[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=3[C:12](=[O:14])[C:13]=2[CH:3]=1参加物
4
実験手順
Chlorine gas is bubbled into a mixture (partial suspension) of 1.0 g (450 mmol) of 5H-dibenz[b,e]azepine-6,11-dione in 50 ml of glacial acetic acid. The temperature of the mixture rises to 38° C. On standing, as the temperature of the solutions decreases, a white solid precipitates. The mixture is filtered to give 0.40 g of solid (mixture of starting material and product in ratio of 1:8). The filtrate on standing gives 0.10 g of product as crystals, m.p. 289°-293° C.
後処理
- customrises to 38° C
- customa white solid precipitates
- filtrationThe mixture is filtered
出典と根拠
- ORDレコード
- ord-abc10a305885403a9bacfadab6b36e20
- 出典データセット
- uspto-grants-1998_06
- 特許番号
- US05760031
反応ノート
読み込み中…