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Acrylonitrile → 3-(3-Iodo-phenylamino)-propionitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acrylonitrile | HCID 7855 | — |
| 反応物 | 3-Iodoaniline | HCID 12271 | — |
| 触媒 | Cupric acetate | HCID 8895 | — |
| 生成物 | 3-(3-Iodo-phenylamino)-propionitrile | HCID 19081634 | 37% |
反応手順
13at) 4.38 g of 3-iodoaniline, 1.06 g of acrylonitrile and 0.5 g of copper-(II)acetate are mixed and held at 70° for 5 hrs. The mixture is chromatographed on silica gel with ethyl acetate/cyclohexane 1:4 and yields 2.01 g of 3-(3-iodo-phenylamino)-propionitrile as a brown oil. Yield: 37%. Mass spectrum: peak inter alia at m/e : 272 (M+, 50%), 232 (100%); 105 (35%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05763450 |
| 出典データセット | uspto-grants-1998_06 |
| ORD ID | ord-c87e1452187a472ab805a0aa8f596f49 |
| 出典メモ | uspto-grants-1998_06 |