関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1-(4-(Trifluoromethyl)phenyl)ethan-1-one | HCID 69731 | — |
| 反応物 | 1,1-Dimethoxyethyl(dimethyl)amine | HCID 87835 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 3-Dimethylamino-1-(4-trifluoromethyl-phenyl)-but-2-en-1-one | HCID 69234633 | — |
反応手順
A mixture of 4′-(trifluoromethyl)acetophenone (9.8 g) and N-(1,1-dimethoxyethyl)-N,N-dimethylamine (8.2 g) was heated at 112° C. overnight, under nitrogen. The reaction mixture was cooled and concentrated giving an orange solid. Trituration with diethyl ether gave the title compound as a yellow solid
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07091237B2 |
|---|
| 出典データセット | uspto-grants-2006_08 |
|---|
| ORD ID | ord-1ea84c7acf084517a9e9625c59ac88bf |
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| 出典メモ | uspto-grants-2006_08 |
|---|
