化工社化工社 化学情報印刷レポート · 研究参考用
Tetrabutylammonium Fluoride → 2,6-Dipropyl-4-vinylphenol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| 反応物 | t-Butyldimethylsilyloxy-2,6-dipropyl-4-vinyl benzene | HCID 19080390 | — |
| 反応物 | Diethylether ethylacetate | HCID 21584169 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 2,6-Dipropyl-4-vinylphenol | HCID 18400414 | — |
反応手順
The title compound was prepared from t-butyldimethyl-silyloxy-2,6-dipropyl-4-vinylbenzene (Step B, Example 14) by treatment with tetrabutylammonium fluoride in THF for a few hours. It was poured into ether/ethyl acetate mixture and washed with brine. After removal of the solvent the crude product was purified by flash column chromatography using ethyl acetate/hexane as eluent.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05767310 |
| 出典データセット | uspto-grants-1998_06 |
| ORD ID | ord-58545c78ce21451da326644a9ef52454 |
| 出典メモ | uspto-grants-1998_06 |