Water → HCID 21986453、化合物

HRID 9654

反応式

HRID 9654 の反応式
[CH2:1]([O:3][C:4](=[O:22])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][C:16]2[S:17][CH:18]=[CH:19][CH:20]=2)=[CH:9][C:8]=1[CH3:21])[CH3:2].[Br:23]Br.O>C(O)(=O)C>[CH2:1]([O:3][C:4](=[O:22])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][C:16]2[S:17][C:18]([Br:23])=[CH:19][CH:20]=2)=[CH:9][C:8]=1[CH3:21])[CH3:2]

参加物

5

反応物 3

HCID 962WaterHCID 24408BromineHCID 21986308Ethyl[2-methyl-4-(2-thien-2-ylethoxy)phenoxy]acetate2 回

生成物 1

HCID 21986453HCID 21986453、化合物

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

A solution of ethyl[2-methyl-4-(2-thien-2-ylethoxy)phenoxy]acetate (intermediate 69, 0.306 g) in acetic acid (5 ml) was treated with bromine (0.180 g) at ambient temperature and the mixture stirred for 15 minutes. The mixture was poured into water and the resulting suspension extracted with diethyl ether. The organic layer was separated, dried over sodium sulfate and concentrated to give the title compound as a colourless oil.

後処理

  1. extractionthe resulting suspension extracted with diethyl ether
  2. customThe organic layer was separated
  3. dry with materialdried over sodium sulfate
  4. concentrationconcentrated

出典と根拠

ORDレコード
ord-7637624903df403d86dd6f4ca5b896ea
出典データセット
uspto-grants-2006_08
特許番号
US07091237B2

関連ノート

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