Ethyl alpha-benzylacetoacetate → HCID 178433370、化合物

HRID 965680

反応式

HRID 965680 の反応式
[CH2:1]([CH:8]([C:14](=O)[CH3:15])[C:9](OCC)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(=O)(O)O.[NH2:21][C:22]([NH2:24])=[NH:23]>C(O)C>[NH2:24][C:22]1[N:23]=[C:9]([OH:10])[C:8]([CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[C:14]([CH3:15])[N:21]=1

参加物

4

反応物 2

HCID 246929Ethyl alpha-benzylacetoacetateHCID 286947Carbonic acid-guanidine (1:1)

生成物 1

HCID 178433370HCID 178433370、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of ethyl 2-benzyl-3-oxobutanoate (6 g, 27.2 mmol), guanidine carbonate (2.94 g, 16.3 mmol) and ethanol (20 ml) was refluxed for 10 hours. After cooling, the precipitate was filtered and washed with water, ethanol and ether in order, to the object compound (3.62 g, 61.7%).

後処理

  1. temperaturewas refluxed for 10 hours
  2. temperatureAfter cooling
  3. filtrationthe precipitate was filtered
  4. washwashed with water, ethanol and ether in order, to the object compound (3.62 g, 61.7%)

出典と根拠

ORDレコード
ord-f19885d0bc5e4cc6916e9d57a48c49c4
出典データセット
uspto-grants-2005_10
特許番号
US06951866B2

関連ノート

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