Dimethyl Sulfate → 6-[2-(4-Methoxy-phenyl)-vinyl]-pyridine-2-carbonitrile
反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[CH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][N+:12]=2[O-])=[CH:5][CH:4]=1.COS(OC)(=O)=O.[C-:25]#[N:26].[Na+]>C(O)(C)C>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[CH:10][C:11]2[N:12]=[C:13]([C:25]#[N:26])[CH:14]=[CH:15][CH:16]=2)=[CH:5][CH:4]=1参加物
5
実験手順
Following the general method described in example 2b, 2-[2-(4-methoxy-phenyl)-vinyl]-pyridine 1-oxide was reacted first with dimethylsulfate and then with NaCN. After extraction and crystallization the title compound was obtained as a yellow crystalline material. Mp. 121-122° C. (isopropanol), MS: m/e=236 (M+)
後処理
- extractionAfter extraction and crystallization the title compound
- customwas obtained as a yellow crystalline material
出典と根拠
- ORDレコード
- ord-5b9a3fd371ec40ae9c1d99c901371cc3
- 出典データセット
- uspto-grants-2005_10
- 特許番号
- US06951875B2
反応ノート
読み込み中…