Hydrazine → HCID 22314380、化合物
反応式
[C:1]([C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([N+:13]([O-])=O)[CH:11]=2)[NH:6][CH:5]=1)(=[O:3])[CH3:2].NN>[Ni].CO>[C:1]([C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([NH2:13])[CH:11]=2)[NH:6][CH:5]=1)(=[O:3])[CH3:2]参加物
5
実験手順
A suspension of 3-acetyl-5-nitroindole (3.0 g, 14.7 mmol) and Raney Nickel (3.0 g) in methanol is treated dropwise with hydrazine (0.7 g, 21.9 mmol) at 0° C., stirred under N2 for 1 h and filtered. The filtrate is concentrated in vacuo to afford the title product as an oil, 2.5 g (99% yield) identified by NMR and mass spectral analyses.
後処理
- filtrationfiltered
- concentrationThe filtrate is concentrated in vacuo
出典と根拠
- ORDレコード
- ord-ff282b7cd89b480790c0b7011fe70c52
- 出典データセット
- uspto-grants-2005_10
- 特許番号
- US06951881B2
反応ノート
読み込み中…