HCID 22314541、化合物 → HCID 69725567、化合物

HRID 966105ノート

反応式

HRID 966105 の反応式
[CH3:1][C:2]([NH:11][CH2:12][C:13]([C:15]1[CH:35]=[CH:34][C:18]2[O:19]C(C3C=CC=CC=3)(C3C=CC=CC=3)[O:21][C:17]=2[C:16]=1[O:36][CH3:37])=[O:14])([CH3:10])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1>Cl>[OH:21][C:17]1[C:16]([O:36][CH3:37])=[C:15]([C:13](=[O:14])[CH2:12][NH:11][C:2]([CH3:1])([CH3:10])[CH2:3][C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)[CH:35]=[CH:34][C:18]=1[OH:19]

参加物

3

反応物 1

HCID 22314541HCID 22314541、化合物

生成物 1

HCID 69725567HCID 69725567、化合物

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒2 回

実験手順

34 g of the HCl salt of 2-(1,1-dimethyl-2-phenylethylamino)-1-(4-methoxy-2,2-diphenylbenzo[1,3]dioxol-5-yl)ethanone is refluxed in 340 mL of 15% methanolic hydrochloric acid for 2 hours. Then the solvent is distilled off under reduced pressure and the residue is dissolved in ethyl acetate. The solid precipitated is suction filtered and washed with ethyl acetate and diethyl ether. Yield: 18 g (77%, hydrochloride); melting point: 192° C.-196° C.

後処理

  1. distillationThen the solvent is distilled off under reduced pressure
  2. dissolutionthe residue is dissolved in ethyl acetate
  3. customThe solid precipitated
  4. filtrationfiltered
  5. washwashed with ethyl acetate and diethyl ether

出典と根拠

ORDレコード
ord-9e9be5236d7448fa8420eea1fceeea77
出典データセット
uspto-grants-2005_10
特許番号
US06951888B2

反応ノート

読み込み中…