N-Methylisopropylamine → {2-{[Isopropyl(methyl)amino]methyl}-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

HRID 9662

反応式

HRID 9662 の反応式
Br[CH2:2][C:3]1[O:4][C:5]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][CH:13]=2)=[CH:6][C:7]=1[C:8]([O:10]C)=O.[CH3:22][NH:23][CH:24]([CH3:26])[CH3:25]>>[CH:24]([N:23]([CH2:2][C:3]1[O:4][C:5]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][CH:13]=2)=[CH:6][C:7]=1[CH2:8][OH:10])[CH3:22])([CH3:26])[CH3:25]

参加物

3

反応物 2

HCID 78485N-MethylisopropylamineHCID 21986318Methyl 2-bromomethyl-5-[4-(trifluoromethyl)phenyl]-3-furoate

生成物 1

HCID 21986358{2-{[Isopropyl(methyl)amino]methyl}-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

実験手順

Prepared using intermediate 44 and N-methylisopropylamine. This compound was used directly without collection of analytical data for the preparation of Example 75.

後処理

  1. customPrepared
  2. customThis compound was used directly without collection of analytical data for the preparation of Example 75

出典と根拠

ORDレコード
ord-0859d51250d044c38378d9f0c267c973
出典データセット
uspto-grants-2006_08
特許番号
US07091237B2

関連ノート

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