Acetic Acid → M-58996
反応式
[ClH:1].C(O)(=O)C.[C:6]([C:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][N:16]2[CH2:21][CH2:20][C:19]([CH2:23][N:24]([CH3:34])[C:25]3[CH:33]=[CH:32][C:28]([C:29]([OH:31])=[O:30])=[CH:27][CH:26]=3)([OH:22])[CH2:18][CH2:17]2)=[CH:10][CH:9]=1)#[N:7]>O>[ClH:1].[C:6]([C:8]1[CH:9]=[CH:10][C:11]([CH2:14][CH2:15][N:16]2[CH2:17][CH2:18][C:19]([CH2:23][N:24]([CH3:34])[C:25]3[CH:26]=[CH:27][C:28]([C:29]([OH:31])=[O:30])=[CH:32][CH:33]=3)([OH:22])[CH2:20][CH2:21]2)=[CH:12][CH:13]=1)#[N:7]参加物
5
実験手順
2N hydrochloric acid (76 μL) was added to an acetic acid solution (100 μL) of the compound (50.0 mg) obtained in Example 14 to prepare homogenous solution. Water (400 μL) was gradually added under stirring and left at rest at room temperature for thirty minutes. The precipitate was collected by filtration and washed with water, ethyl acetate and ether successively, and dried to obtain the titled compound (48.2 mg) as crystals.