化工社化工社 化学情報印刷レポート · 研究参考用
4-[4-(Trifluoromethyl)phenyl]thiophene-3-carbaldehyde → Phenyl{5-[4-(trifluoromethyl)phenyl]thien-3-yl}methanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-[4-(Trifluoromethyl)phenyl]thiophene-3-carbaldehyde | HCID 21986376 | — |
| 反応物 | 1-{5-[4-(Trifluoromethyl)phenyl]thien-3-yl}ethanol | HCID 21986431 | — |
| 反応物 | HCID 178418255 | HCID 178418255 | — |
| 生成物 | Phenyl{5-[4-(trifluoromethyl)phenyl]thien-3-yl}methanol | HCID 21986317 | — |
反応手順
The title compound was prepared using a method analogous to that used for the preparation of 1-{5-[4-(trifluoromethyl)phenyl]thien-3-yl}ethanol (intermediate 126) using 4-[4-(trifluoromethyl)phenyl]thiophene-3-carbaldehyde (intermediate 125) and phenyl magnesium bromide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07091237B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-2336788b038b41e689f66b799d3c2b1d |
| 出典メモ | uspto-grants-2006_08 |