Sodium 4-methylbenzenesulfonate → 4-Methylphenylbenzylpiperidinium tosylate

HRID 968172

反応式

HRID 968172 の反応式
[Br-].[CH3:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]2([CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]2)=[CH:5][CH:4]=1.[C:22]1([CH3:32])[CH:27]=[CH:26][C:25]([S:28]([O-:31])(=[O:30])=[O:29])=[CH:24][CH:23]=1.[Na+]>O>[S:28]([C:25]1[CH:26]=[CH:27][C:22]([CH3:32])=[CH:23][CH:24]=1)([O-:31])(=[O:30])=[O:29].[CH3:2][C:3]1[CH:4]=[CH:5][C:6]([N+:9]2([CH2:15][C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]2)=[CH:7][CH:8]=1

参加物

4

反応物 2

HCID 3720192Sodium 4-methylbenzenesulfonateHCID 865888244-Methylphenylbenzylpiperidinium bromide

生成物 1

HCID 865888254-Methylphenylbenzylpiperidinium tosylate収率 91,980.203%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

An aqueous solution prepared by dissolving 4-methylphenylbenzylpiperidinium bromide (13.85 g, 0.04 mmol) and sodium p-toluenesulfonate (9.32 g, 0.048 mmol) in 50 ml of deionized water was extracted with 50 ml of chloroform twice by using a separating funnel. The resulting chloroform phases were combined and the combined solution was washed with 50 ml of deionized water, followed by filtration and drying to obtain 4-methylphenylbenzylpiperidinium tosylate (16.1 g, yield: 92%).

後処理

  1. customAn aqueous solution prepared
  2. extractionwas extracted with 50 ml of chloroform twice
  3. washthe combined solution was washed with 50 ml of deionized water
  4. filtrationfollowed by filtration
  5. customdrying

出典と根拠

ORDレコード
ord-b93f0cc87f6a45a998414276fb93508a
出典データセット
uspto-grants-2005_10
特許番号
US06958205B2

関連ノート

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