化工社化工社 化学情報印刷レポート · 研究参考用
HCID 10910823、化合物 → Spermine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | HCID 10910823 | HCID 10910823 | — |
| 反応物 | TriBoc-Spermine | HCID 22610912 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 生成物 | Spermine | HCID 1103 | — |
反応手順
Monoquaternary spermine containing hydrophilic head-group was prepared in a similar way to compound 3. Briefly, TriBoc-Spermine was reacted with excess of 1-azido-3-iodo-propane in the presence of excess TBA. The resulting quaternarized derivative was hydrogenised under (Pd—C) and Boc protecting group were removed using gaseous HCl in dry methanol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06958325B2 |
| 出典データセット | uspto-grants-2005_10 |
| ORD ID | ord-7efc57ded6f7404794f1c0a62996d328 |
| 出典メモ | uspto-grants-2005_10 |