Toluene → (3S,4S)-3-bromomethyl-1-tert-butoxycarbonyl-4-fluoropyrrolidine

反応式

[Br:1][CH2:2][CH:3]1[CH2:4][N:5]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:6][CH:7]1[OH:8].[CH3:56][c:57]1[cH:58][cH:59][cH:60][cH:61][cH:62]1.[F:27][C:28]([F:29])([S:30]([F:31])(=[O:32])=[O:33])[C:34]([F:35])([F:36])[C:37]([F:38])([F:39])[C:40]([F:41])([F:42])[C:43]([F:44])([F:45])[C:46]([F:47])([F:48])[C:49]([F:50])([F:51])[C:52]([F:53])([F:54])[F:55].[N:16]12[CH2:17][CH2:18][CH2:19][N:20]=[C:21]1[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]2>>[Br:1][CH2:2][CH:3]1[CH2:4][N:5]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:6][CH:7]1[F:27]