1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → 5-[3-(4-(4-(4-Fluorophenyl)methylphenyl)piperazin-1-yl) propylsulfamoyl]-2,3,4,5-tetrahydro-1-benzoxepine
反応式
Cl[CH2:2][CH2:3][CH2:4][NH:5][S:6]([CH:9]1[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[O:13][CH2:12][CH2:11][CH2:10]1)(=[O:8])=[O:7].[F:20][C:21]1[CH:26]=[CH:25][C:24]([CH2:27][C:28]2[CH:33]=[CH:32][C:31]([N:34]3[CH2:39][CH2:38][NH:37][CH2:36][CH2:35]3)=[CH:30][CH:29]=2)=[CH:23][CH:22]=1>>[F:20][C:21]1[CH:22]=[CH:23][C:24]([CH2:27][C:28]2[CH:33]=[CH:32][C:31]([N:34]3[CH2:35][CH2:36][N:37]([CH2:2][CH2:3][CH2:4][NH:5][S:6]([CH:9]4[C:15]5[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=5[O:13][CH2:12][CH2:11][CH2:10]4)(=[O:8])=[O:7])[CH2:38][CH2:39]3)=[CH:30][CH:29]=2)=[CH:25][CH:26]=1参加物
3
実験手順
The compound (10) synthesized in Reference Example 10 and the compound (5) synthesized in Reference Example 5 were used to produce the above compound in the same way as Example 1.
後処理
- customto produce the above compound in the same way as Example 1