{2-Ethyl-4-[({2-methyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetic acid → {2-Chloro-4-[({2-methyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetic acid
反応式
C([O:3][C:4](=[O:18])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([S:13](Cl)(=O)=O)=[CH:9][C:8]=1[Cl:17])C.C(C1C=C(S[CH2:33][C:34]2[CH:38]=[C:37]([C:39]3[CH:44]=[CH:43][C:42]([C:45]([F:48])([F:47])[F:46])=[CH:41][CH:40]=3)[O:36][C:35]=2[CH3:49])C=CC=1OCC(O)=O)C>>[Cl:17][C:8]1[CH:9]=[C:10]([S:13][CH2:33][C:34]2[CH:38]=[C:37]([C:39]3[CH:40]=[CH:41][C:42]([C:45]([F:48])([F:46])[F:47])=[CH:43][CH:44]=3)[O:36][C:35]=2[CH3:49])[CH:11]=[CH:12][C:7]=1[O:6][CH2:5][C:4]([OH:3])=[O:18]参加物
3
実験手順
The title compound was prepared from ethyl[4-(chlorosulfonyl)-2-chlorophenoxy]acetate (intermediate 113) by a method analogous to that used for the preparation of {2-ethyl-4-[({2-methyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetic acid (example 145).
出典と根拠
- ORDレコード
- ord-08e0beb152404f3a8b4579a391103cbc
- 出典データセット
- uspto-grants-2006_08
- 特許番号
- US07091237B2
反応ノート
読み込み中…