4-(1,1-Dimethoxyethyl)pyrimidin-2-amine → 1-(2-Aminopyrimidin-4-yl)ethan-1-one
反応式
C[O:2][C:3]([C:7]1[CH:12]=[CH:11][N:10]=[C:9]([NH2:13])[N:8]=1)(OC)[CH3:4]>C(O)=O>[NH2:13][C:9]1[N:8]=[C:7]([C:3](=[O:2])[CH3:4])[CH:12]=[CH:11][N:10]=1参加物
3
実験手順
To 4-(1,1-dimethoxy-ethyl)-pyrimidin-2-ylamine (Step A, 15 g, 81.87 mmol) was added HCOOH (70.0 mL). The resulting mixture was stirred at RT under argon for 3 h. The mixture was evaporated to dryness. The solid was recrystallized from EtOH to give a brown solid. MS m/z:138.2(M+H). Calc'd for C6H8N3O: 138.14.
後処理
- customThe mixture was evaporated to dryness
- customThe solid was recrystallized from EtOH
- customto give a brown solid
出典と根拠
- ORDレコード
- ord-50ad7417d71c4cf89b8701774ce486b6
- 出典データセット
- uspto-grants-2007_12
- 特許番号
- US07307088B2
反応ノート
読み込み中…