Dimethylformamide dimethyl acetal → HCID 74015821、化合物
反応式
[Cl:1][C:2]1[N:3]=[C:4]2[CH:9]=[CH:8][C:7]([Cl:10])=[N:6][N:5]2[C:11]=1[S:12]([NH2:15])(=[O:14])=[O:13].CO[CH:18](OC)[N:19]([CH3:21])[CH3:20]>C1(C)C=CC=CC=1>[Cl:1][C:2]1[N:3]=[C:4]2[CH:9]=[CH:8][C:7]([Cl:10])=[N:6][N:5]2[C:11]=1[S:12]([N:15]=[CH:18][N:19]([CH3:21])[CH3:20])(=[O:14])=[O:13]参加物
4
実験手順
2,6-Dichloroimidazo[1,2-b]pyridazin-3-ylsulfonamide (2.00 g, 6.22 mmol) and N,N-Dimethylformamide dimethyl acetal (1.80 ml, 13.5 mmol) were heated under reflux for 4 hours in toluene (20.0 ml). The resulting reaction solution was left to cool to room temperature, and concentrated to dryness under reduced pressure to give the title compound as pale yellow crystals. The yield was 2.36 g (100%).
後処理
- customThe resulting reaction solution
- waitwas left
- concentrationconcentrated to dryness under reduced pressure
出典と根拠
- ORDレコード
- ord-995eaf41e8404746bb2c92b5623e7e9d
- 出典データセット
- uspto-grants-2007_12
- 特許番号
- US07307165B2
反応ノート
読み込み中…